Arkamin H tablets combine two active ingredients: Clonidine hydrochloride (0.1 mg) and Hydrochlorothiazide (12.5 mg). Here's a comprehensive description of Arkamin H tablets:

• Active Ingredients:

  • Clonidine hydrochloride: It is a centrally acting alpha-2 adrenergic agonist. Clonidine acts on alpha receptors in the brain to reduce sympathetic outflow, leading to decreased peripheral resistance, lowered heart rate, and reduced blood pressure.
  • Hydrochlorothiazide: It is a thiazide diuretic that works by inhibiting sodium reabsorption in the distal convoluted tubules of the kidneys, promoting diuresis (increased urine production) and reducing fluid volume, which helps lower blood pressure.

• Indications: Arkamin H tablets are primarily used for the management of hypertension (high blood pressure). The combination of Clonidine and Hydrochlorothiazide helps control blood pressure by different mechanisms: Clonidine by reducing sympathetic tone and Hydrochlorothiazide by promoting diuresis.

• Dosage: The usual dosage of Arkamin H tablets can vary depending on the individual's condition and response to treatment. Typically, one tablet is taken orally once daily. Dosage adjustments may be necessary based on blood pressure monitoring and individual patient response.

• Administration: Arkamin H tablets are meant to be taken orally with water. They can be taken with or without food.

• Precautions:

  • Arkamin H tablets should be used cautiously in patients with impaired kidney function.
  • Regular monitoring of blood pressure and electrolytes (especially potassium levels) is recommended during therapy.
  • Avoid sudden discontinuation of Clonidine as it may lead to rebound hypertension.
  • Hydrochlorothiazide can cause electrolyte imbalances (e.g., low potassium levels), so periodic monitoring is important.

• Side Effects: Common side effects of Arkamin H tablets may include dizziness, dry mouth, drowsiness, constipation, and electrolyte disturbances. Serious side effects such as severe allergic reactions or significant decreases in blood pressure can occur but are rare.

• Storage: Store Arkamin H tablets at room temperature away from moisture and heat. Keep them out of reach of children.

Arkamin H tablets are prescription medications used under the supervision of a healthcare provider. It's important to follow the prescribed dosage and instructions provided by your doctor to achieve optimal blood pressure control and minimize potential side effects.